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Reducing time to transplant through increased donor cell collection availability

A cell collection centre with a live booking system increases infrastructure capacity and scheduling flexibility for stem cell donors, better meeting patient needs; the right donor at the right time.

  • Proposal
  • 2024

Meet the team

Also:

  • Elizabeth King - Project Manager
  • Abi Ibrahim - Business Analyst

What is the challenge your project is going to address and how does it connect to the theme of 'How can we improve across system boundaries?​

Anthony Nolan is a key provider of unrelated donor stem cells, however a growth in transplant numbers and stem cell treatments for other conditions has resulted in an increased need for donated stem cells, and growing pressure on the current donation infrastructure we rely on.

Difficulties in booking donation slots at the required time results in a delay for the patient, meaning clinicians must choose whether to wait and opt for further chemotherapy or move on to a potentially less optimal donor from overseas.

We will address the crisis in cell collection capacity through the establishment of a new centre for cell collection, with capacity to facilitate the entire process; medically screen donors, facilitate cell collection, and process these donations for transport to transplant and research centres, ultimately improving time to transplant for patients.

What does your project aim to achieve?

Establishing a cell collection centre, within an NHS Trust, specifically for the donation of stem cells; including the setting up of operational and clinical processes, necessary regulatory and accreditation approvals, recruitment and training of staff (increasing staffing numbers within both the NHS and Anthony Nolan) and purchasing of equipment to enable the delivery of a first-class service.

The cell collection centre processes will feature an integrated live scheduling system allowing the Anthony Nolan Donor Provision team to coordinate both donor availability and the transplant or research centre’s requested dates, mitigating the current need to consult back and forth multiple times with existing providers and the selected donor all within a critical timeframe.

This will rapidly increase efficiency and drive up the percentage of UK donations able to be made on the first date requested by transplant centres, reducing time to transplant, and therefore positively impacting patient outcomes.

How will the project be delivered?

Project managed by Anthony Nolan, in partnership with an existing NHS Trust, and drawing on internal and external expertise, we will establish the clinical infrastructure required to set up a cell collection facility.

To ensure we deliver an improved and more efficient process, that ensures an increase in the number of donors donating on the date requested by the Transplant Centre, it is critical that a live scheduling system is developed, customisable and integrated with our existing Donor Provision processes.

Following a process of requirements gathering, process mapping, system short-listing, selection, configuring and user acceptance testing we will identify and deliver a fit-for-purpose live scheduling system. Working in parallel with the clinical infrastructure elements of the project, we will ensure the booking system is delivered ahead of project go-live, in order to be validated live alongside the clinical processes on site.

How is your project going to share learning?

Going forwards, we hope to utilise the scheduling tool data and outputs to further increase the proportion of donors donating on the date the Transplant Centre requests, by identifying trends where we have been unable to meet these dates. This learning could influence a number of aspects of the operational management of stem cell donation, from donor availability to transplant centre relationship management.

The Anthony Nolan Cell Collection centre will become part of an existing network of centres across the UK, and as we strive to become a centre of excellence both clinically and operationally, we hope that our learnings can be shared across this network.

As we develop the centre and deepen our partnership with the NHS, we will look to provide insight to the Q Community about the development. This may take the form of a lessons learned presentation, a show and tell or similar activity.

How you can contribute

  • While we believe we have the skills within Anthony Nolan and with our NHS partner, we will seek to use the network as a critical friend as we design the necessary supporting processes and ways of working. Ensuring that we meet quality standards is our top priority and there is significant quality expertise across the network which we would seek to tap into as we develop the proposal and deliver the project.

Plan timeline

1 Jul 2023 Discovery phase
1 Nov 2023 Planning phase
1 Jan 2024 Engagement and defining operational agreements with host Trust
1 Jan 2024 Process mapping and requirements gathering
1 Feb 2024 Sourcing and selecting a scheduling tool to support operational requirements
1 Apr 2024 Configuring, testing and implementing scheduling tool
1 Apr 2024 Delivering operating model to be able to establish the service
1 Jul 2024 Engaging with Transplant Centre stakeholders
1 Jul 2024 Testing and validating processes and procedures
1 Oct 2024 Go live and the start of cell collection
1 Nov 2024 Reflection, lessons learned and continuous improvement processes established